Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta is a delightful dish that brings together the bold flavors of Cajun spices, tender chicken, and a creamy mozzarella Alfredo sauce. Whether you’re hosting a family dinner or preparing a cozy meal for yourself, this recipe promises to impress with its rich taste and satisfying textures. The combination of twisted pasta and savory chicken makes it a perfect choice for any occasion.

Jump to:
- Why You’ll Love This Recipe
- Tools and Preparation
- Essential Tools and Equipment
- Importance of Each Tool
- Ingredients
- For the Chicken
- For the Pasta
- For the Sauce
- For Garnish
- How to Make Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Step 1: Boil the Pasta
- Step 2: Cook the Chicken
- Step 3: Make the Sauce
- Step 4: Combine Cheeses
- Step 5: Mix Everything Together
- Step 6: Serve
- How to Serve Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Pair with a Fresh Salad
- Add Some Crunch
- Enhance with Garnishes
- How to Perfect Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Best Side Dishes for Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Common Mistakes to Avoid
- Storage & Reheating Instructions
- Refrigerator Storage
- Freezing Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Reheating Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Frequently Asked Questions
- Can I use different proteins for this recipe?
- What type of pasta works best?
- How spicy is Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta?
- Can I make this dish ahead of time?
- What’s a good side dish for Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta?
- Final Thoughts
- 📖 Recipe Card
Why You’ll Love This Recipe
- Quick and Easy: This dish can be prepared in just 30 minutes, making it perfect for busy weeknights.
- Rich and Flavorful: The Cajun seasoning adds a unique kick, while the creamy Alfredo sauce brings comfort and indulgence.
- Versatile: Serve it as a hearty main course or pair it with a fresh salad for a balanced meal.
- Family-Friendly: The cheesy goodness appeals to both kids and adults, ensuring everyone will enjoy it.
- Leftover Magic: This dish tastes just as good the next day, making it ideal for meal prep or leftovers.
Tools and Preparation
Before diving into cooking, gather your essential tools. Having the right equipment streamlines the process and ensures success.
Essential Tools and Equipment
- Large pot
- Skillet
- Colander
- Measuring cups and spoons
- Knife and cutting board
Importance of Each Tool
- Large pot: Necessary for boiling pasta efficiently while allowing enough space for movement.
- Skillet: Ideal for cooking chicken evenly and creating the creamy sauce in one pan.
- Colander: Helps drain pasta quickly without losing any delicious noodles.
- Knife and cutting board: Essential for slicing chicken and prepping garlic easily.

Ingredients
For the Chicken
- 1.25 lbs boneless, skinless chicken breasts, sliced into strips
- 1 tbsp olive oil
- 1 tbsp Cajun seasoning (plus extra to taste)
- 1 tsp garlic powder
- Salt & black pepper, to taste
For the Pasta
- 12 oz twisted pasta (like rotini or fusilli)
For the Sauce
- 2 tbsp butter
- 4 cloves garlic, minced
- 1 cup chicken broth
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- 2 oz cream cheese (for extra creaminess)
For Garnish
- Chopped parsley
How to Make Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
Step 1: Boil the Pasta
Bring a large pot of salted water to a boil.
1. Cook the twisted pasta until al dente according to package instructions.
2. Drain the pasta in a colander but reserve about ½ cup of pasta water for later use.
Step 2: Cook the Chicken
Season the sliced chicken with Cajun seasoning, garlic powder, salt, and pepper.
1. Heat olive oil in a large skillet over medium-high heat.
2. Add the seasoned chicken strips to the skillet.
3. Cook for about 5-6 minutes until golden brown and cooked through.
4. Transfer cooked chicken to a plate and set aside.
Step 3: Make the Sauce
In the same skillet used for chicken:
1. Melt butter over medium heat.
2. Add minced garlic; cook for about 1 minute until fragrant.
3. Stir in chicken broth and heavy cream, scraping up any browned bits from the bottom of the skillet.
Step 4: Combine Cheeses
Lower heat before adding:
1. Cream cheese, shredded mozzarella, and grated Parmesan cheese.
2. Stir continuously until cheeses melt into a smooth sauce; if too thick, add reserved pasta water gradually.
Step 5: Mix Everything Together
Return both cooked pasta and chicken back to the skillet.
1. Toss everything together until well coated in sauce.
2. Let simmer for about 2 minutes so flavors meld together beautifully.
Step 6: Serve
Garnish with chopped parsley before serving hot.
For an extra indulgent touch, top with additional mozzarella cheese before serving!
How to Serve Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
Serving Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta is all about enhancing the flavors and creating a delightful dining experience. Here are some creative serving suggestions to elevate your meal.
Pair with a Fresh Salad
- Mixed Greens Salad: A simple salad of mixed greens, cherry tomatoes, and a light vinaigrette adds freshness to the rich pasta dish.
- Caesar Salad: Crisp romaine lettuce with creamy dressing and croutons complements the creamy sauce beautifully.
Add Some Crunch
- Garlic Bread: Warm, buttery garlic bread is perfect for scooping up the creamy Alfredo sauce.
- Crispy Roasted Vegetables: Roasting seasonal vegetables like Brussels sprouts or carrots adds texture and balances the richness of the pasta.
Enhance with Garnishes
- Fresh Herbs: Sprinkle chopped parsley or basil on top for a pop of color and added flavor.
- Extra Cheese: Serve with additional shredded mozzarella or Parmesan on the side for cheese lovers.
How to Perfect Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
To master this delicious dish, consider these helpful tips for an exceptional cooking experience.
- bold seasoning: Adjust the Cajun seasoning to your taste. Start with the recommended amount and add more if you prefer a spicier kick.
- bold pasta doneness: Cook the twisted pasta until al dente, as it will continue to cook when mixed with the sauce. This ensures a perfect texture.
- bold cheese choice: Use high-quality cheeses for a creamier and richer sauce. Freshly grated cheeses melt better than pre-shredded options.
- bold simmering time: Allow the combined dish to simmer for a couple of minutes after tossing. This helps meld all flavors together beautifully.
- bold reserved pasta water: Keep some reserved pasta water handy. It’s great for adjusting sauce thickness without losing flavor.
- bold garnish wisely: Don’t skip on garnishing! Fresh herbs or extra cheese can make your dish visually appealing and add extra flavor.
Best Side Dishes for Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
Pairing side dishes with your main course can enhance your meal’s overall appeal. Here are some fantastic options that work well alongside Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta.
- Garlic Mashed Potatoes: Creamy mashed potatoes infused with garlic make for an indulgent side that complements any creamy dish.
- Grilled Asparagus: Lightly seasoned grilled asparagus adds a smoky flavor and vibrant color to your plate.
- Coleslaw: A crunchy coleslaw provides a refreshing contrast to the creamy pasta while adding some crunch.
- Roasted Sweet Potatoes: Naturally sweet roasted sweet potatoes balance out the savory flavors of the chicken and pasta.
- Steamed Broccoli: Simple steamed broccoli is nutritious and provides a nice green contrast to the rich dish.
- Corn on the Cob: Grilled or boiled corn on the cob brings sweetness and fun to any dinner table, making it a family favorite.
- Caprese Skewers: Cherry tomatoes, mozzarella balls, and basil drizzled with olive oil serve as an elegant finger food option before your main course.
- Baked Zucchini Fries: Crispy baked zucchini fries offer a healthy alternative that’s still satisfying alongside your creamy pasta dish.
Common Mistakes to Avoid
Cooking Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta can be a delightful experience, but there are some common pitfalls to watch out for.
- Using too much Cajun seasoning: While it adds flavor, too much can overpower the dish. Start with one tablespoon and adjust to taste.
- Not cooking the pasta al dente: Overcooked pasta can become mushy and lose its texture. Always follow package instructions and taste test before draining.
- Skipping the reserved pasta water: This starchy water helps the sauce cling better to the pasta. Don’t forget to set some aside before draining!
- Not letting flavors meld: Allowing the dish to simmer for a few minutes after combining ingredients enhances the overall flavor. Don’t rush this step!
- Using cold chicken straight from the fridge: For even cooking, let your chicken come closer to room temperature before cooking. It ensures more consistent results.

Storage & Reheating Instructions
Refrigerator Storage
- Store in an airtight container.
- Keep in the refrigerator for up to 3 days.
Freezing Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Use freezer-safe containers or bags.
- Can be frozen for up to 2 months for best quality.
Reheating Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Oven: Preheat to 350°F (175°C) and heat in a covered dish until warmed through, about 20-25 minutes.
- Microwave: Place in a microwave-safe bowl, cover loosely, and heat on medium power in 1-minute intervals until hot.
- Stovetop: Heat in a skillet over medium-low heat, stirring occasionally until heated through. Add a splash of broth if needed.
Frequently Asked Questions
Here are some common questions about making Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta.
Can I use different proteins for this recipe?
Yes! You can substitute chicken with turkey or even beef if you prefer a different flavor profile.
What type of pasta works best?
Twisted pasta like rotini or fusilli is ideal because it holds onto the creamy sauce well. However, you can use any pasta shape you like.
How spicy is Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta?
The spice level depends on how much Cajun seasoning you use. Start mild and adjust according to your taste preferences!
Can I make this dish ahead of time?
Yes! You can prepare it ahead of time, store it, and reheat it when ready to serve.
What’s a good side dish for Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta?
A simple green salad or steamed vegetables pairs wonderfully with this rich pasta dish.
Final Thoughts
Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta is not only delicious but also versatile. You can customize it by adding vegetables like spinach or bell peppers for extra nutrition. Give this recipe a try and enjoy the incredible flavors!
Did You Enjoy Making This Recipe? Please rate this recipe with ⭐⭐⭐⭐⭐ or leave a comment.
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Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta
- Total Time: 30 minutes
- Yield: Serves 4
Description
Cajun Garlic Chicken with Creamy Mozzarella Alfredo Twisted Pasta is a mouthwatering dish that combines the zest of Cajun spices with tender chicken and a rich, creamy sauce. Perfect for busy weeknights, this meal can be prepared in just 30 minutes, making it an ideal choice for families or anyone craving comforting flavors. The twisted pasta holds onto the luscious mozzarella Alfredo sauce beautifully, ensuring every bite is satisfying. Garnished with fresh parsley, this dish not only delivers on taste but also looks appealing on your dinner table.
Ingredients
- 1.25 lbs boneless, skinless chicken breasts
- 1 tbsp olive oil
- 1 tbsp Cajun seasoning (plus extra to taste)
- 1 tsp garlic powder
- Salt & black pepper, to taste
- 12 oz twisted pasta (like rotini or fusilli)
- 2 tbsp butter
- 4 cloves garlic, minced
- 1 cup chicken broth
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- 2 oz cream cheese (for extra creaminess)
- Chopped parsley
Instructions
- Boil a large pot of salted water and cook the twisted pasta until al dente. Drain and reserve some pasta water.
- Season chicken strips with Cajun seasoning and garlic powder. In a skillet, heat olive oil over medium-high heat and cook chicken until golden brown. Set aside.
- In the same skillet, melt butter and sauté minced garlic until fragrant. Add chicken broth and heavy cream, scraping the skillet's bottom.
- Lower heat and mix in cream cheese, mozzarella, and Parmesan until melted into a smooth sauce.
- Combine cooked pasta and chicken into the sauce, tossing until well-coated. Allow to simmer for two minutes.
- Serve hot, garnished with chopped parsley.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Category: Main
- Method: Cooking
- Cuisine: Cajun
Nutrition
- Serving Size: 1 serving
- Calories: 630
- Sugar: 3g
- Sodium: 680mg
- Fat: 38g
- Saturated Fat: 21g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 42g
- Fiber: 2g
- Protein: 36g
- Cholesterol: 150mg





